Hi everyone just got a mgus diagnosis and wanted to see if anyone could help me make heads or tails of all this info.
The doctor was really vague with his answer. I do know I do not have a lytic lession on the back of my head.
If someone could please help and not sugar coat anything thank you.
BONE MARROW, ASPIRATION AND BIOPSY:
- NORMOCELLULAR MARROW WITH TRILINEAGE HEMATOPOIESIS
- MONOCLONAL PLASMACYTOSIS WITH KAPPA LIGHT CHAIN RESTRICTION, PLASMA CELLS CONSTITUTE APPROXIMATELY 5-7% OF MARROW CELLS, CONSISTENT WITH PLASMA CELL DYSCRASIA (SEE DESCRIPTION AND COMMENT)
- MORPHOLOGIC FEATURES NOT DIAGNOSTIC FOR MYELODYSPLASTIC SYNDROME
- SEE GENETIC REPORT IN KP HEALTHCONNECT
COMMENT: Correlation with clinical, laboratory, and imaging features is suggested.
POSITIVE for the IGH-FGFR3 t(4;14) translocation (55% of isolated plasma
POSITIVE for monosomy 13/deletion 13q14.3 (28% of isolated plasma cells).
NEGATIVE for the following: deletion of CDKN2C (1p), gain of CKS1B (1q)
and/or gain of chromosome 1, gain/loss of chromosomes 5, 11, and 17,
partial deletion of chromosomes 5q (EGR1), 16q (MAF), and 17p (TP53),
translocations of IGH-CCND1 t(11;14) and IGH-MAF t(14;16).