Hi @SunFlower,
One of our brill Blood Cancer UK nurses, Gemma, answered a similar question about cladribine in another, older thread here and I think it might be useful for you.
She covers what to expect around infection risk and how neutropenic sepsis is managed - in short, your husband’s team will give you both clear guidance, but it typically means taking his temperature at home if he feels unwell, and calling the team straight away if it’s over 37.5°C so they can review him quickly.
you might also find it useful to look at Cancer Research UK’s information on cladribine as a drug and at our own Blood Cancer UK page on treatment for hairy cell leukaemia as well.
You’re right that the question about how much the experience varies is the kind of thing the community here can speak to so much better than simple information pages can, and I hope some members with direct experience of hairy cell leukaemia and cladribine will be along soon to share their perspectives.
Our Support Line is there for both of you if you’d like to talk anything through, and is staffed by our nurses: 0808 2080 888 (option 1) or support@bloodcancer.org.uk.
Keep posting whenever you need to,
Ceri - Blood Cancer UK Support Services