Hi she has been having fortnightly blood transfusions and starts treatment on Monday on Venetoclax and azacitidine on a 7 day cycle repeated monthly has any one out there been on this treatment and how is this administered and what are the usual side affects also she has been suffering with hives and when she scratches them they turn into boil like spots. Any advice on how to manage them would be appreciated
Hi @Barington Welcome to the forum.
I’m sorry to hear that your partner has been diagnosed with Acute myeloid leukaemia ('AML').
When I was first diagnosed with Myelofibrosis I was on Azacitidine on the 7 day cycle that you describe.
It was injections for this 7 day cycle each month.
Day 1 injection to arm, Day 2 injection into stomach and Day 3 injection into legs.
They then rotate round in the same order until end of the cycle.
My condition progressed to Acute myeloid leukaemia ('AML') and after unsuccessful High Intensity Chemo I was moved on to Venetoclax and Azacitidine combination.
Azacitidine administered as above.
Venetoclax was a tablet every day for each 28 day cycle.
On the whole it was very manageable. What I found with the Azacitidine was that if I had my injection late on the first day of the cycle I had a bit of sickness sometimes.
In terms of the hives I can’t offer any advice. I would however recommend you and your partner discuss with your clinical team as they are best placed to advise in terms of her situation.
The Venetoclax and Azacitidine combination appears to be a good option and it was the first treatment that helped get my blasts down to a point where I could have a Bone Marrow Transplant.
Hope that helps.
2 Likes
Thank you DuncanB appreciate the input
3 Likes
Hello there @Barington, welcome to the forum. I’m really sorry to read of your partner’s diagnosis. It’s lovely that you’re here to support her, and I hope the forum can offer you support too.
While I live with a different blood cancer to Acute myeloid leukaemia ('AML'), called Polycythaemia vera ('PV'), mine can progress to Acute myeloid leukaemia ('AML') so I try to learn what I can. Thank you for coming here as you will no doubt help others, and I see dear @DuncanB has shared his own lived experiences.
Perhaps you’ve seen it already but here is the great Blood Cancer UK information about Acute myeloid leukaemia ('AML'): Acute myeloid leukaemia (AML) - what it is, symptoms, tests, treatment, prognosis and support. | Blood Cancer UK
If you’d like to read how other forum members are doing with their Acute myeloid leukaemia ('AML') and treatments you could use the search box at the top or check Related Topics at the bottom. I know there are many members like @DuncanB who have shared around the forum.
Hope that helps @Barington, do let us know how you both get on.
3 Likes
Thank you Duncan I appreciate the support of others going through the same
3 Likes